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LNCap-Nuc
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LNCap-Nuc Description
Nuclear extract obtained from LNCap cells. Can be used for transcription and splicing in vitro assays.
LNCap cells are a cell line of human cells commonly used in the field of oncology. LNCaP cells are androgen-sensitive human prostate adenocarcinoma cells derived from the left supraclavicular lymph node metastasis. They are adherent epithelial cells growing in aggregates and as single cells. The malignant properties of LNCaP cells are maintained in the cell culture. The cells present a hormonally responsive model of cancer. High-affinity specific androgen receptors are present in the cytosol and nuclear fractions of cells in culture and in tumors. Estrogen receptors are found in the cytosol. The cell line expresses Prostate Specific Antigen).